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Severe influenza versus pandemic influenza: <br />I. Pandemic Flu II Seasonal Flu I <br />Rarely happens (three times in 20th Happens annually and usually peaks in January or <br />century) February <br />People have little or no immunity because Usually some immunity built up from previous <br />they have no previous exposure to the virus exposure <br />Healthy people may be at increased risk for Usually only people at high risk, not healthy adults, <br />serious complications are at risk of serious complications <br />Health care providers and hospitals may be Health care providers and hospitals can usually <br />overwhelmed meet public and patient needs <br />Vaccine probably would not be available in Vaccine available for annual flu season <br />the early stages of a pandemic <br />Effective antivirals may be in limited Adequate supplies of antivirals are usually available <br />supply <br />Number of deaths could be high (The U.S . Seasonal flu-associated deaths in the United States <br />death toll during the 1918 pandemic was over 30 years ending in 2007 have ranged from <br />approximately 675,000) about 3,000 per season to about 49,000 per season. I Symptoms may be more severe I Symptoms include fever, cough, runny nose, and <br />muscle pam <br />May cause major impact on the general Usually causes minor impact on the general public, <br />public, such as widespread travel some schools may close and sick people are <br />restrictions and school or business closings encouraged to stay home <br />Potential for severe impact on domestic and Manageable impact on domestic and world <br />world economy economy <br />61